ANGIOFIBROMA JUVENIL PDF

ANGIOFIBROMA JUVENIL PDF

Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas. Introduction: Juvenile nasopharyngeal angiofibroma (NAJ) is a tumor with .. Acessos Cirúrgicos no Angiofibroma Nasofaríngeo Juvenil – Relato de caso e. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally aggressive fibrovascular tumor arising from the posterolateral wall of the.

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Histopathology reveals a fibrocellular stroma with spindle cells and haphazard arrangement of collagen interspersed with an irregular vascular pattern. Oronasal fistula a possible complication of preoperative embolization in the management of juvenile nasopharyngeal angiofibroma. Tumour extension produces rhinosinusal symptoms and facial swelling. The prevalence in males may be explained by high androgen receptor AR expression suggesting that JNA is androgen dependent. If nasopharyngeal angiofibroma is suspected based on physical examination a smooth vascular submucosal mass in the posterior nasal cavity of an adolescent maleimaging studies such as CT or MRI should be performed.

Improvements in surgical techniques are designed to shorten surgical time and thereby reduce patient morbidity. No encapsulation was noted [ Figure 4 ]. You can change the settings or obtain more information by clicking here.

Lastly, if the involvement of the anterior fossa or planum sphenoidale is very broad or intradural, a craniofacial or subcranial approach with acceptable morbidity can be used.

Juvenile nasopharyngeal angiofibroma | Radiology Reference Article |

Involvement of cavernous sinus, hypophysis or optic chiasm. The remaining 17 patients, regardless of the tumor classification, underwent embolization and clamping of the external carotid arteries due to better control of bleeding during surgery.

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Spontaneous regression of untreated JNA has been observed only ocasionally. Initially used to treat diseases such as non-neoplastic polyps and sinus disease, the development of the technique enabled the excision of benign and malignant tumors located more recently 5.

Results Analysis was performed on 42 males and one female. New author database being installed, click here for details. Open in a separate window. Juvenile nasopharyngeal angiofibroma JNA is a vascular tumour arising most often near the sphenopalatine orifice. Case 5 Case 5.

Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Invasion of the intracranial region may lead to cranial nerve palsy. Invasion of the pterygopalatine fossa, maxillary sinus, ethmoid or sphenoid, with bone destruction.

Juvenile nasopharyngeal angiofibroma JNA is a benign neoplasm of the nasopharynx. Another recent study of Schlauder et al suggests that the enzyme aromatase is responsible for local conversion of androgens to estrogens, which in turn relates to the role of estrogen receptors in tumor growth It presents as an innocuous, painless, unilateral nasal obstruction with or without epistaxis and rhinorrhea.

It is an angiifibroma neoplasm and shows a propensity for destructive local spread often extending to the base of the skull and into the cranium. Two patients received radiosurgery, anigofibroma of which responded well and the other remained with a stable tumour.

Angiofibroma nasofaríngeo juvenil – Wikipedia, la enciclopedia libre

Acta Otolaryngol,pp. Similarly, our patients ranged in age from 10 to 29 years, with a mean age of 16 years, and all were male. Traditionally, the NAJ has been parched by transfacial, transoral or combined craniofacial access.

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Ann Otol Rhinol Laryngol, 93pp. Markers of vascular differentiation, proliferation and tissue remodeling in juvenile nasopharyngeal angiofibromas.

Juvenile nasopharyngeal angiofibroma

However, recent studies angiofibrooma failed to show any usefulness. Arch Otolaryngol Head Neck Surg,pp. The mean age at diagnosis was 16 years, which was similar to that reported by other series. The Journal of Laryngology and Otology.

The study population consisted of 43 patients undergoing surgery. Nasopharyngeal angiofibroma is a histologically and biologically benign tumor with aggressive behavior due to its location and associated symptoms including significant epistaxis and nasal obstruction The location and size of the tumor and feeding vessels are clearly demonstrated by this technique. The tumor invades the nasal sinuses or the pterygomaxillary fossa with bone destruction.

Angiofibroma nasofaríngeo juvenil

Nasal endoscopy, alone or combined with open techniques, was safe for the resection of angiofibromas at different stages, with low morbidity and high efficacy, as shown by complete tumor removal and low recurrence rates.

Case 7 Case 7. Ujvenil and young adults between 14 and 25 years are affected, and there is a distinct male predominance.